Although the basic of MRSI are already explained in the RF sequence e-module, still several Neuro methods and items applied in Proton Spectroscopy are added. Some CEST methods are discussed more in depth than others like APT. Sodium Imaging can give some direct and quantitative biochemical information on the tissue viability, study of metabolism, cell integrity and function, and therefore not only help the diagnosis but also the prognosis of diseases and treatment results. Techniques and applications of all 3 methods are discussed.